Hello! I am a computational biophysicist specialised in developing minimal and coarse-grained models for biomolecules. During my PhD I worked on Fluctuating Finite Element Analysis, and I'm currently working in the Collepardo Lab at Cambridge on phase separation of Chromatin. You can get in touch with me at [email protected]. While you're here, please take a look at my CV and LinkedIn profile!
Max Everdrive is a sitcom I wrote in the early stages of the pandemic (mostly in April-May 2020). It's an attempt to capture the feeling of the time, alongside a more general exploration of science, pop-culture and hauntology. It's about a suicidally depressed talking dog searching for a new home after the destruction of Earth. You can download the scripts for all 6 episodes.
During 2021 I worked as a senior research software engineer on the MOLPRO, quantum chemistry package. This post details my work on optimising and profiling MOLPRO's linear algebra libraries, and the results.
Regolith is a screenplay I wrote in August 2021.
Genre: Horror/Sci-Fi/Alt-History
Logline: A dysfunctional group of NASA astronauts are pursued by a hostile entity as they attempt to uncover the dark secrets of the moon.
License: CC BY-NC-SA 4.0
Download Regolith
KOBRA is a fluctuating Kirchoff elastic rod algorithm for performing dynamical simulations of slender biomolecules, such as alpha-helices and coiled-coils. It can support parameterisations of objects with arbitrary equilibrium shapes and inhomogeneous, anisotropic material parameters, and it can reach second-scale trajectories of quite large systems on modest workstation hardware. It's written in C++ and is released, for free, under the GPLv3 free software license. So far, KOBRA has been used to build models of Ndc80C, the SMC complex and Myosin-V, and may soon be deployed to study COVID-19 spike proteins. This page will contain links to the KOBRA publication, my PhD thesis, download links and installation instructions.
I had intended to give this presentation over the spring and summer of 2020, but I only got to give it once in person. It's a quick overview of the KOBRA algorithm and software, with some discussion of Ndc80c and the kinetochore.
Hell Bent is a tale of crime and redemption beyond life and death. This is a feature length screenplay for a supernatural comedy/crime movie. I wrote this in 2016 in a span of around three weeks, as a writing experiment. It is available under CC BY-NC-SA 4.0. Logline: An aging mobster concocts a plan to steal ambrosia from the gods, but ends up fighting to save his soul. Download Hell Bent
The Sound of Max Everdrive is my third album, a collection of ambient and experimental music written for the apocalypse by myself and M. Richard Talley. You can download it for free.
‘Never Obsolete’, my second album, a compilation of music featuring old synthesizers and samples. From the quiet hiss of the Yamaha CS-80 to the crackle of a 4-channel Amiga module, Never Obsolete is a celebration of the old technology that helped to shape modern music. It’s also pay-what-you-want, open-source, and all of the proceeds go toward charities focused on archiving and preserving digital information and protecting software freedom.
I gave this presentation at the 2017 Visegrad Symposium at Nove Hrady, Czechia, and again in 2018 at the CompBioMed AHM. It's a quick overview of the FFEA algorithm and software package.
FFEA is a continuum mechanics biophysics simulation package designed for large, complex systems of biomolecules. It had been in use at Leeds for a few years (mostly for simulations of the motor protein Dynein), but now it's free software that anyone can download. In this article I'll talk about my work on the software so far and on the FFEA software publication in PLOS CompBio.